Factors influencing metal concentrations in hair and nails during longitudinal follow-up of apprentice welders

Type de document

Études primaires

Année de publication

2024

Langue

Anglais

Titre de la revue

Journal of Toxicology and Environmental Health - Part A: Current Issues

Première page

1030

Dernière page

1049

Résumé

The aim of this study was to determine factors influencing observed increased metal biomarkers of exposure levels in a group of 116 Quebec apprentice welders during a longitudinal follow-up of exposure. Analysis of 14 metals was carried out in hair, fingernail, and toenail samples taken from participants over the course of their welding curriculum at 6 different times. Personal and socio-demographic characteristics, lifestyle habits, and other potential confounding factors were documented by questionnaire. Multivariate linear mixed-effect models were used to assess main predictors of metal concentrations in each biological matrix including increasing time of exposure throughout the curriculum (defined as the repeated measure “time” variable”). Significant associations between repeated measure “time” variable and metal levels in hair, fingernails, and toenails were found for chromium, iron, manganese and nickel. Significant associations with “time” were also noted for arsenic levels in hair and fingernails, and for barium, cobalt and vanadium levels in fingernails and toenails. The repeated measure “time” variable, hence increasing time of exposure throughout the curriculum, was the predominant predictor of elevated biological metal levels. Reduced spaces and simultaneous activities such as oxyfuel-cutting and welding in the same welding room were suspected to contribute to higher metal levels. Age, ethnicity, and annual household income exerted an effect on metal levels and considered as confounders in the models. Variations observed in metal levels between hair and nails of apprentice welders also emphasized the relevance and importance of performing multi-matrix and multi-element biomonitoring to assess temporal variations in biological metal concentrations during welding curriculum. © 2024 Taylor & Francis Group, LLC.

Mots-clés

Fumée de soudage, Welding fume, Soudage et coupage à l'arc, Arc welding and cutting, Évaluation de l'exposition, Exposure evaluation, Expérience, Experience, Étudiant, Student, Dosage dans les ongles, Determination in fingernails, Dosage dans les cheveux, Determination in hair, Échantillonnage dans l'air, Air sampling, Étude longitudinale, Longitudinal study

Numéro de projet IRSST

2019-0003

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