ORCID
France Labrèche http://orcid.org/0000-0001-8722-0433
Type de document
Revues de littérature, synthèses de connaissances
Année de publication
2024
Langue
Anglais
Titre de la revue
Reviews on Environmental Health
Résumé
Introduction
Our objective was to identify published, peer-reviewed, epidemiological studies that estimated associations between the risk of developing or dying from malignant breast cancer and past exposure to selected organic solvents with reactive metabolites, to delineate the methods used and to synthesize the results.
Content
We undertook a structured review of case-control and cohort studies used to investigate breast cancer risk and exposure to selected organic solvents that produce reactive metabolites in the body. We used SCOPUS, MEDLINE (Ovid) and Web of Science databases from 1966 to December 31, 2023 to identify epidemiological studies that estimated associations between the risk of developing or dying from malignant breast cancer and past exposure to selected organic solvents with reactive metabolites and organic solvents combined as a group.
Summary
We described essential methodological characteristics of the 35 studies and presented quantitative results by individual solvent and other characteristics. We did not find compelling evidence that any of the selected organic solvents are implicated in the etiology of breast cancer.
Outlook
As millions of workers are exposed to organic solvents, this topic necessitates further investigation. Future research should focus on elucidating organic solvents that may contribute to the burden of breast cancer.
Mots-clés
Cancer du sein, Breast cancer, Solvant organique, Organic solvents, Exposition, Exposure, Épidémiologie, Epidemiology
Numéro de projet IRSST
2017-0038
Citation recommandée
Westra, S., Goldberg, M. S., Labrèche, F., Baumgartner, J. and Ho, V. (2024). A structured review of the associations between breast cancer and exposures to selected organic solvents. Reviews on Environmental Health. https://doi.org/10.1515/reveh-2024-0051
Included in
Epidemiology Commons, Neoplasms Commons, Occupational Health and Industrial Hygiene Commons